On 6 December 2024 we will be releasing the Q4 API changes for the VarSome API (stable-api.varsome.com).
The Stable API will update version 12.1.1 to version 12.6.0 with data frozen as of the 2 November 2024. This version has been successfully used in production for over a month.
The most recent version, used by VarSome itself, is always available at api.varsome.com.
Database Updates
The following databases have been updated:
|
Source |
Data Type |
Current (Stable, Q3 '24) |
Next Release (Staging, Q4 '24) |
|
AACT |
gene |
03-Jul-2024 |
04-Oct-2024 |
|
ACMG classifier |
variant |
12.1.1 |
12.5.1 |
|
AMP classifier |
variant |
12.1.1 |
12.5.1 |
|
ClinVar |
variant |
05-Jul-2024 |
04-Oct-2024 |
|
ClinVar |
region / CNV |
05-Jul-2024 |
04-Oct-2024 |
|
CPIC |
gene |
03-Jul-2024 |
04-Oct-2024 |
|
dbNSFP |
variant |
4.8 |
4.9 |
|
dbNSFP |
gene |
4.8 |
4.9 |
|
gene2phenotype |
gene |
03-Jun-2024 |
04-Oct-2024 |
|
GWAS |
variant |
03-Jul-2024 |
06-Sep-2024 |
|
LOVD |
variant |
17-Jun-2024 |
17-Oct-2024 |
|
ClinGen |
Disease Validity |
03-Jul-2024 |
04-Oct-2024 |
|
ClinGen |
variant |
03-Jul-2024 |
04-Oct-2024 |
|
ClinGen |
gene |
03-Jul-2024 |
04-Oct-2024 |
|
ClinGen |
region / CNV |
03-Jul-2024 |
04-Oct-2024 |
|
OMIM |
gene |
17-Jun-2024 |
16-Sep-2024 |
|
OMIM |
variant |
17-Jun-2024 |
16-Sep-2024 |
|
PharmGKB |
gene |
03-Jul-2024 |
04-Oct-2024 |
|
PharmGKB |
variant |
03-Jul-2024 |
04-Oct-2024 |
|
PMKB |
variant |
03-Jul-2024 |
04-Oct-2024 |
|
DECIPHER |
region / CNV |
03-Jul-2024 |
04-Oct-2024 |
|
Known Pathogenic |
gene |
05-Aug-2024 |
02-Nov-2024 |
|
Known Pathogenic |
variant |
05-Aug-2024 |
02-Nov-2024 |
|
UniProt Regions |
regions |
03-Jun-2024 |
04-Oct-2024 |
|
Uniprot Variants |
variant |
03-Jun-2024 |
04-Oct-2024 |
|
HPO |
disease |
03-Jul-2024 |
06-Sep-2024 |
|
GHR |
gene |
03-Jul-2024 |
04-Oct-2024 |
JSON Schema Changes
Variants
API Request
No changes.
Genes
No changes.
CNVs
No changes.
Reminder: all the data structures returned by the VarSome API are documented:
For variants here.
For genes here.
For CNVs here.
Please contact us if you need any further assistance with this release.
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